|Cyclobenzaprine 10mg (Gen. for Flexeril) 180 Tabs||$169||free||$169||Order|
Cyclobenzaprine is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) that are sent to your brain.
Cyclobenzaprine is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.
Cyclobenzaprine may also be used for purposes not listed in this medication guide.
Meta-analysis studies have found significantly increased rates of drowsiness (38% of patients), dry mouth (24%), dizziness (10%), and adverse events of any kind in patients taking cyclobenzaprine versus placebo. Drowsiness and dry mouth appear to intensify with increasing dose.
The sedative effects of cyclobenzaprine are likely due to its antagonistic effect on histamine, serotonin, and muscarinic receptors. Agitation is a common side effect observed especially in the elderly. In general, the NCQA recommends avoiding the use of cyclobenzaprine in the elderly because of the potential for more severe side effects. There is one case report of overdose causing rhabdomyolysis (muscle breakdown). Treatment protocols and support should follow the same as for any structurally related tricyclic, such as tricyclic antidepressants.
Before taking this medicine
Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
You should not use cyclobenzaprine if you are allergic to it, or if you have:
- a heart rhythm disorder, or you have recently had a heart attack;
- congestive heart failure;
- heart block; or
- a thyroid disorder.
To make sure cyclobenzaprine is safe for you, tell your doctor if you have:
- liver disease;
- enlarged prostate; or
- problems with urination.
Older adults may be more sensitive to the side effects of this medication.